LASTING EFFECTS OF DRUG EXPOSURE ON BRAIN ACTIVITY
Exposure to drugs, particularly during periods of brain development, is a significant risk factor for neurological and psychiatric disorders. We focus on understanding the mechanisms responsible for these conditions, and on developing strategies to ameliorate or even prevent their occurrence. We study the consequences of exposure, during development, to opioids, nicotine, and marijuana. In separate studies we investigate changes in the brain that occur during withdrawal from opioids, in an attempt to understand how to reduce the negative symptoms that lead to relapse.